Why pregnancy does not develop in the early stages. Reliable signs of non-developing pregnancy. Manifestations of non-developing pregnancy

Undeveloped pregnancy - unfortunately, more and more often such a diagnosis began to overshadow the happy existence of pregnant women. It happens that a very desired and long-awaited pregnancy freezes, stops developing. According to statistics, in the life of about 20% of women expecting a baby, such a tragedy happens, and it can happen at any time. Such a horrific event should be able to survive every woman who has been diagnosed with this. This article will present the symptoms, causes, and all other aspects of a missed pregnancy.

In the process of researching the causes of pregnancy fading, it was found that in a certain period of time, pregnancy is most vulnerable:

  1. The first 12 days of development, during this period, implantation occurs.
  2. After that, at week 3, the period of embryogenesis begins, which lasts until week 8.
  3. All 12 first weeks, when the placenta is formed, is also a vulnerable period.
  4. At 20-24 weeks, the formation and development of the most important functions of the fetus occurs.

Symptoms of non-developing pregnancy

  • In early pregnancy, one of the symptoms is the cessation of hCG growth ( chorionic gonadotropin person). This hormone is produced due to the chorion, and various conclusions can be drawn from its indicators. During pregnancy, the growth of this hormone is usually not monitored. But this can be done on your own by donating blood for an hCG analysis. It will also be relevant to do a pregnancy test, with a missed pregnancy it will be negative.
  • Abrupt cessation of signs of toxicosis. Signs gradually fade away within 2 months, and when the embryo dies, nausea stops immediately.
  • The swelling of the mammary glands stops, if the swelling was accompanied by pain, they also stop.
  • Termination of the growth of the uterus. At each scheduled examination, the gynecologist leading the pregnancy takes measurements of the size of the uterus. If the size does not correspond to the term, there are suspicions that the pregnancy has stopped in development. A low-lying bottom of the uterus may also indicate the fading of the fetus.
  • Pain in the lower abdomen and red or reddish-brown discharge from the genital tract can also indicate the onset of a miscarriage, but this case does not always indicate that the fetus has died.
  • Absence of heartbeat on examination and ultrasound. In the early stages up to 6 weeks, the embryo can be considered dead if heart rhythms are not detected on ultrasound. Anembryony is a pathology when the fetus dies at a very early stage, when even ultrasound does not fix it. This is evidenced by an empty fetal egg.
  • Absence or cessation of movement. From 18 to 20 weeks, every pregnant woman should already begin to feel the movements of her baby. If these are not observed, the woman is urgently sent for an ultrasound scan, the same is done with those whose fetus moved, but during the day the woman stops feeling the tremors.


Causes of non-developing pregnancy

The beneficial development of pregnancy depends on many aspects, and a deviation in even one of them often leads to irreparable consequences. The causes of pregnancy fading may be associated with:

  • Infection in the mother's body. Diseases that a woman had in the past, and with the onset of pregnancy for the first time worsened, these can be viral, bacterial and fungal diseases. The uterus may have been affected by an infection in the past, in connection with which the ovum may not be able to successfully attach to the affected uterus, and the pregnancy will fail. Or an infection that has entered the bloodstream through the genitals, enters the embryo, this leads to its death.
  • Hormonal background. The hormonal background changes a lot with the onset of pregnancy, and there are times when these fluctuations go in the wrong direction. So, the hormone progesterone can be produced in insufficient quantities. Elevated levels of male hormones can also adversely affect the successful course of pregnancy.
  • endocrine disorders. The endocrine system is strongly linked to the hormonal system. If, due to a hormonal imbalance, a pregnant woman has problems with weight, an excessive increase or decrease, this affects the functioning of the thyroid gland. The state of pregnancy depends on its proper operation.
  • Immunological incompatibility of the fetus and mother. When one of the parents has Rh negative blood, the fetus can inherit this trait. Such a combination of circumstances often leads to the fact that the mother's organism sees a foreign body in the developing embryo. This leads to the fact that the fetus is rejected.
    Bad habits. These include not only smoking and alcoholic beverages, but also improper, unhealthy diet or lack of nutrition. Pregnancy largely depends on these factors. The circulation of blood in the placenta, the nutrition of the fetus and its development directly depend on the lifestyle of the mother.
  • Prolonged depression, constant stress is directly related to the development of the baby.
  • Also at risk are women with an anatomically deformed uterus.
  • Women who have had several abortions may also face such a problem in the future as a non-developing pregnancy.
  • According to statistics, a pregnancy that occurs with the help of IVF often ends in fading than natural fertilization.



Complications of non-developing pregnancy

Consequences occur when the dead fetus remains in the body of a woman for a long time.

  1. It could be endometritis. In this case, inflammation of the uterine mucosa occurs.
  2. The process of decomposition of the fetus can lead to sepsis and peritonitis.


Ways to remove an undeveloped pregnancy

When this terrible diagnosis is confirmed, the question arises of how to solve this problem. Several options for further action are possible.

  • Wait. After the fetus dies hCG level in the blood begins to fall, which after a while leads to the expulsion of the fetus from the body. But a long wait is fraught with consequences, so after a few days another option is considered.
  • Medical interruption. This option is available up to 8 weeks. The patient takes the drug, and, after a while, a spontaneous miscarriage occurs.
  • Vacuum aspiration. Vacuum cleaning is a surgical intervention when the pregnancy has stopped for a long time, and threatens with complications for the woman's body.
  • Curettage or curettage is used in the same cases as a vacuum.
    The last two options are performed under local or general anesthesia.



Prevention of non-developing pregnancy

To reduce the likelihood of premature termination of pregnancy to a minimum, you must follow some rules.

  1. Finding out the cause of fetal fading - pathogenetic factors.
  2. It is necessary to eliminate these factors or minimize their manifestation in future pregnancies.
  3. Get your mental and emotional state in order. There is no need to be shy or afraid to consult a psychologist. A positive attitude is essential for a healthy pregnancy. If necessary, sedatives should be taken.
  4. Visits to the gynecologist should be regular.



New pregnancy. When is it possible?

After a pregnancy with a sad end, some women for a long time cannot recover, decide on a new one. But there are those who see their "salvation" in a new pregnancy. Such women almost immediately ask themselves the question “when is it already possible?”.
After a non-developing pregnancy, a woman's body needs time to be rehabilitated. You need to wait for the body to recover and get stronger. This will take from six months to one and a half years.
It is worth taking this time to find out the cause of the fading of the last pregnancy, to actively engage in the restoration and treatment of the body.


conclusions

Naturally, after such a blow of fate, every woman asks herself: “why with my child? Why with me?" Do not get hung up on this, because nature knows best what to do. Factors such as natural selection, the struggle for existence are the driving forces of evolution, and they apply to everything, including humans!

In 90% of cases, after one missed early or late pregnancy, you can get pregnant again. And it will end with a long-awaited and timely meeting with a dear baby.

It is worth remembering that planning for pregnancy is no less important period than the pregnancy itself. Much depends on the quality of planning. It is worth paying special attention to this period and thoroughly preparing for the onset of the long-awaited situation.
A woman in position must be careful and attentive to her condition. You should take all tests in a timely manner, follow the recommendations of doctors and, of course, your intuition.

Never lose hope! The first meeting with the baby is worth all the problems through which life leads us!


How beautiful pregnant women are! But sometimes an inexorable fate brings down terrible and unbearable trials on their shoulders.

One of them is non-developing pregnancy, the death of the unborn baby.

This can happen at any stage of pregnancy. This pathology occurs in 10-20% of cases.

In contact with

Crisis periods are identified when the fetus is most vulnerable to negative impacts:

  • 7-12 days of development (implantation period);
  • 3- development (the period of embryogenesis);
  • the first (formation of the placenta);
  • 20- development (formation of the most important functions in the body of the fetus).

The most dangerous are the first days and weeks of baby development. In the early stages of its development, the fetus is most sensitive to damaging, destructive factors.

What should alert a pregnant woman?

Diagnosis of the disease

Signs and symptoms

In most cases, a stop in the development of a child is not felt by pregnant women and is not accompanied by pronounced symptoms.

In the early stages:

  • disappearance;
  • increase in appetite;
  • reduction of pain in the mammary glands.

At a later date:

  • the appearance of bleeding;
  • increase in body temperature;
  • drawing pains in the lower back.

Such signals can accompany the normal course of pregnancy. Only a specialist can finally confirm the death of the embryo through ultrasound and research. Who is to blame for failed motherhood?

The reasons

As a rule, a frozen pregnancy is the result of a combination of unfortunate circumstances and factors.

The reasons can be divided into several groups.

Genetics. Sometimes, during the formation of an embryo, various changes occur in the chromosomes, genetic disorders (a larger or smaller set of chromosomes).

The reason for this may be hereditary predisposition, the use of drugs, alcohol, living in environmentally unsafe areas.

Genetic disorders are the most important causes of this pathology (up to 70% of all cases). "Wrong" genes can come from both parents.

Infections. Infectious diseases future mother is the second most common cause of non-developing pregnancy:

  • viral -, enterovirus;
  • bacterial - mycoplasmas, streptococci, gonococci, chlamydia, ureaplasmosis.

As a result of the presence of any infection in a pregnant woman, acquired or chronic, infection of the fetal egg occurs.

Infection can occur in three ways:

  1. In the inflammatory process of the uterine mucosa and its appendages(endometritis, salpingoophoritis) microbes penetrate the fetal egg. In this case, the woman’s uterus itself is not ready to bear a child, the fetal egg is not attached tightly enough, and its rejection follows.
  2. With inflammatory processes in the vagina itself(fungi,) bacteria penetrate to the fetal egg through the cervix. The embryo becomes infected and amniotic fluid, which is fraught with rupture of the fetal bladder itself.
  3. With past viral infections(, ORZ,) microbes penetrate to the fetal egg with blood flow through the placenta. Significantly deteriorating supply of oxygen and nutrients to the unborn baby

When infected, the fetus stops its development, the child dies.

Do not forget that pregnancy is accompanied by a strong suppression of the entire immune system. An exacerbation of all latent infectious diseases in a woman may begin.

Therefore, it is very important to treat all latent infections in time before planning motherhood and do everything possible so as not to catch a cold while pregnant.

Immunology. Sometimes a woman may have various predisposing factors that can cause the death of the embryo. This is the appearance of protective antibodies to the hormone produced by the fetal egg (antiphospholipid syndrome), incompatibility at the immune level of the father and mother.

Immunological incompatibility can be expressed by increased thrombus formation. In all cases, the nutrition of the embryo is disturbed, its development stops and the fetus dies.

Endocrinology. The pathological state of the endocrine system of a pregnant woman can provoke the death of the fetus. Causes of disruption of the proper functioning of the endocrine system and hormonal disorders there may be many.

The most common of them are:

  • an increased amount of sex hormones according to the male type (hyperandrogenism). In 20% of cases during pregnancy, there is a sharp jump in the level of male hormones.
  • an increased amount of a hormone that stimulates milk production (hyperprolactinemia).
  • violation proper development ovary (), which affects menstrual cycle and production of female sex hormones.
  • improper functioning of the thyroid gland (dystrophy, obesity).
  • underdevelopment of the female reproductive organs (infantilism).

In case of violations of the endocrine system the body produces insufficient amounts of a hormone that is responsible for the preparation of everything female body to pregnancy. An embryo that is weakly attached to the uterus receives insufficient nutrients and dies.

Women are at risk who lead an incorrect lifestyle that is harmful to the state of pregnancy. Constant stress, overstrain, long depression. Work in unsuitable conditions (high humidity, constant stuffiness).

All this can lead to the appearance and abruption of the placenta, which disrupts the supply of oxygen and nutrients to the fetus and, as a result, the death of the unborn baby.

Multiple abortions, transferred . Woman's age(in case of the first one), features of the anatomical structure of the uterus(saddle-shaped,) - all this refers to the provoking factors for the appearance of pathology during pregnancy.

According to the observations of experts, a pregnancy, compared to a natural one, is more likely to turn into a dead one and end in the death of the embryo.

What awaits a woman who has had one or more unsuccessful pregnancies, what do doctors say about this?

Consequences of non-developing pregnancy

As a rule, the vast majority of women have every chance to conceive a child again and bear it safely.

According to statistics, this is 80-90% of all women who have experienced a missed pregnancy.

If the conception ended in the death of the fetus in two or more cases of pregnancy, then the non-developing pregnancy goes into the category of "habitual".

In this case, in order to safely endure the baby, a thorough examination of both spouses is required.

Pregnancy after an illness

Planning for the next pregnancy resolved six months after the failure.

This break is aimed at the complete restoration of the hormonal status, reproductive functions of the body and includes the following mandatory examinations:

  • Ultrasound of the pelvic organs;
  • PCR diagnostics (detection of urogenital infections);
  • blood test for the level of autoantibodies,;
  • blood test to detect antibody titer to;
  • determination of the level of thyroid hormones in the blood.

This list can have many more items. An individual examination plan is applied to each woman, which is prescribed by a gynecologist.

But how is an undeveloped pregnancy treated, what do doctors do in this case?

Treatment of non-developing pregnancy

If a frozen fetus is found in a pregnant woman, doctors develop tactics for taking measures for delivery, based on each specific case.

Spontaneous. Shortly after the death of the embryo, the level of placental hormones in a woman decreases sharply, which leads to an independent miscarriage.

With the help of medicines. In early miscarriages (before 8 weeks), doctors may use the mifepristone (progesterone) antagonist drug in combination with misoprostol (an analogue of prostaglandin E1). After these two drugs enter the body, the embryo is rejected, it is miscarried.

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Frozen or not developing called such a pregnancy in which the death of the embryo or fetus occurred before development, but does not develop contractile activity and there are no symptoms of external bleeding. In this case, the fetal egg can linger in the uterine cavity for many weeks and even months.

information Missed pregnancy occurs in 45-90% of all spontaneous abortions in the early stages. In the International Classification of Diseases of the X revision, this pathology is called "missed miscarriage."

Allocate 2 options this pathology:

  1. . In this case, the embryo is not laid at all or resolves (detected before -), while the fetal sac may grow for some time before the onset of spontaneous miscarriage due to the remaining blood flow.
  2. Doom embryo (before) or fetus (-).

The reasons

The causes of fetal death are diverse and often intertwined. The main ones are the following:

  1. Infection. But there are 2 options here:
    • In acute infection in early pregnancy, direct damage to the embryo by infectious agents occurs.
    • The presence of chronic inflammation leads to disruption of the process of introduction of the fetal egg into the wall of the uterus and disruption of its blood supply. All this leads to primary placental insufficiency and, ultimately, to the death of the fetus.
  1. Hormonal disorders. It is believed that pronounced violations of the hormonal status of a woman lead to infertility, and pregnancy is possible only with erased forms of pathology, but it most often ends with an interruption at one time or another. The main forms of hormonal disorders leading to a missed pregnancy include:
    • with an inferior function of the corpus luteum, production decreases (the main hormone that supports pregnancy);
    • increased production of androgens (male sex hormones);
    • (especially the increase in her hormone levels);
    • neuroendocrine syndromes.
  1. development reproductive organs, preventing the normal growth and development of the embryo.
  2. Chromosomal abnormalities. Occur as a result of a violation of the process of fusion of maternal and paternal material.
  3. Blood coagulation disorders. This includes antiphospholipid syndrome, when antibodies to platelets are produced in the mother's body and thrombosis occurs in the vessels that feed the fetal egg.
  4. Socio-biological factors: in recent decades, there has been a significant deterioration of the ecological environment ( different kinds pollution, for example, radiation and chemical); poor living conditions ( unbalanced diet, deficiency); a variety of occupational hazards that can affect both before the onset of pregnancy and at its initial stages; mother's age.

Symptoms

In the early stages (before), the main clinical manifestation will be the disappearance of subjective (morning sickness and vomiting, salivation). At a later date, these symptoms lose their relevance, since normally they should already pass and the absence or cessation of sensation comes to the fore. On the 3-6th day after the embryo development stops, the mammary glands soften and milk is released from them.

dangerous When a dead fetus is in the uterus for more than 4 weeks, some women show signs of general intoxication (weakness, malaise, fever) associated with infection of the fetal egg.

Signs such as absence, appearance from the genital tract (as a sign of what has begun) appear most often only 6 weeks after the embryo has stopped developing.

Diagnostics

sign early term late deadline
Reducing the blueness of the vagina and cervix4-5 weeks after embryo deathAfter 6-8 weeks
Reduction or lag of the uterus in sizeMore typicalLess typical
Opening of the cervical canalNot1-2 cm
from the cervical canal when viewed in the mirrorsMore often absent, but very rarely there may be minor saniousWhen a dead fetus is in the uterine cavity for more than 4 weeks -
-signsThere is no embryo in the fetal egg after pregnancy or is not determined
  • absence ;
  • fetal inconsistency;
  • abnormal position of the fetus;
  • pronounced changes in .
(chorionic gonadotropin) in the bloodReduced by 8 times compared to normal pregnancyReduced by 3 times

Treatment

Treatment of a missed pregnancy includes 2 main points:

  • careful removal of the dead fetal egg from the uterine cavity;
  • anti-inflammatory therapy.

The method of evacuation of the fetal egg depends on the gestational age:

  • Up to 14-16 weeks produce instrumental emptying of the uterine cavity () or. The resulting material must be sent for histological examination. At the same time, in some cases it is possible to determine why the embryo has ceased to develop.
  • At term over 16 weeks special solutions are injected into the amniotic cavity, and intravenous drugs that stimulate uterine contractions are also administered. After the incident, scraping is performed.

additionally AT recent times there have been works on the application hormonal drugs in . These include 2 groups of drugs: (cause detachment of the fetal bladder) and (contribute to the removal of the contents of the uterine cavity).

This technique, of course, is more gentle for a woman, but it is difficult to obtain material for research and there is a risk of complications from taking these drugs.

Effects

All the consequences of a frozen pregnancy can be divided into two groups:

  • arising against the background of a non-developing pregnancy and in the near future after the removal of the fetal egg;
  • appearing later.

If we talk about the first, then most often they are infectious in nature and depend on where the pathogens got:

  • With the localization of the process only in the uterus, acute endometritis can develop.. And after treatment of a non-developing pregnancy, due to the fact that the inflamed uterus is not able to adequately contract, blood clots linger in the cavity, and repeated curettage will be required.
  • With a long stay of a dead embryo or fetus in the uterine cavity, peritonitis may develop when infectious agents enter the abdominal cavity, or sepsis if they enter the bloodstream.
  • Early consequences also include severe disorders in the coagulation system. in women, which is associated with the ingress of toxic products into the blood.

As for the second group, they primarily depend on the cause of the fading and the correct approach to its treatment and rehabilitation. The possibility of subsequent pregnancy and its outcome will depend on this. According to studies, during rehabilitation in the postoperative period, pregnancy occurs in 85% of cases and ends in childbirth in 70%, without rehabilitation treatment - in 83 and 18%, respectively.

Conclusion

In conclusion, it should be noted that no matter how hard this loss was, this is not a point in history, but only a sad stage. Everything will be fine, the main thing is to take care of your health.

What every woman should know about missed pregnancy

A frozen or non-developing pregnancy is a pregnancy in which development stops, and then the death of the fetus in the early stages due to a violation of the normal course of pregnancy.

Non-developing pregnancy can occur early and up to 28 weeks of pregnancy. But the most dangerous period This is the first trimester of pregnancy.

The timing of a frozen pregnancy

In most pregnant women, a missed pregnancy occurs before 12 weeks of gestation. But after 12 and up to 28 weeks it is less common.

A missed pregnancy can occur both with the first pregnancy and after the second and third successfully completed pregnancy.

What is the danger of frozen pregnancy

The danger of a frozen pregnancy lies in the fact that if the fetus after death is in the body of a woman for a long time, intoxication (poisoning) of the body of the pregnant woman develops. The body temperature begins to rise, unpleasant or painful sensations appear in the uterine cavity. A woman feels weakness throughout her body, malaise, often dizziness and the appearance of drowsiness.

If the embryo after death is in the uterine cavity for more than seven weeks, then this leads to DIC syndrome (disseminated intravascular coagulation).

The clotting properties of the circulatory system lose their ability to coagulate blood, and as a result, massive bleeding from the uterine cavity opens - a complication of non-developing pregnancies. The onset of bleeding can be fatal (unless, of course, qualified medical care is not provided to a pregnant woman at the time).

In some cases - successful cases for a woman's health, the body of a pregnant woman is able to reject the fetus itself after it stops developing - the woman begins a spontaneous miscarriage.

In some cases, a non-developing pregnancy can pass for quite a long period of time without any symptoms and signs.

Signs of a missed pregnancy in the early stages

But still, there are several signs by which it is possible to determine the onset of an undeveloped (frozen) pregnancy.

In the early stages of pregnancy, with the death of the fetus or fetal egg, decline basal body temperature - body temperature, which is measured in the rectum. With the help of basal temperature, hormonal fluctuations are determined. As the hormone rises, the temperature rises. Therefore, the pregnancy progresses. The decline tells us otherwise.

- Indicators (human chorionic gonadotropin) stop rising. In dynamics, the growth of the hormone stops or increases slightly in comparison with the normative indicators - which indicates the pathology of the development of a normal pregnancy.

- Brown or bloody discharge from the genital tract- this is the first signal that something went wrong during a normal pregnancy. It is necessary to immediately contact your doctor to make the correct diagnosis and prescribe the appropriate treatment for a pregnant woman.

- Appearances of general malaise, drowsiness or a feeling of coldness in the body, accompanying muscle trembling. A number of such signs indicate poisoning of the body with decay products that enter directly into the mother's blood.

- An increase in body temperature. An increase in temperature indicates that in the body of a pregnant woman begins inflammatory process and the body can no longer cope on its own. Immediate medical intervention is required.

- Stopping Breast Enlargement. The hormone progesterone decreases and, consequently, the increase (swelling) of the mammary glands decreases or disappears.

- Pain in the lower abdomen of a different nature(aching, cutting, pulling, stabbing or cramping). Usually, pain begins to bother a woman on the fifth - seventh day after the death of the unborn baby.

In women with early toxicosis(nausea, vomiting) - sharp, fast without any reason for it termination also speaks of a deviation in the course of the development of a progressive pregnancy.

- Delayed growth of the uterus(the size of the uterine cavity does not correspond to the set gestational age). To do this, the attending physician monitors the growth dynamics of the uterine cavity every visit to a pregnant woman.

The most reliable and accurate sign - stop or absence of fetal heartbeat which is recorded on an ultrasound machine.

- In the second trimester, a sign of a missed pregnancy is the cessation (absence) of the unborn baby moving. It is for these purposes that doctors prescribe a pregnant woman to monitor the physical activity of her baby during the day. With the help of perturbation, one can judge the condition of the fetus.

Why does an undeveloped pregnancy occur?

Doctors identify three main causes of this pathology.

1. Genetic (chromosomal damage) fetal pathology

Genetic pathology occurs in early pregnancy from six to eight weeks of pregnancy. But sometimes the fetus can live and develop until later in pregnancy. There is a pathological formation of internal organs or systems in the embryo. Chromosomal damage leads to a stop in the development and death of the embryo.

An anomaly in the development of the fetus can occur both in completely healthy parents and can be inherited from one of the parents. With the condition that one of the parents has a certain genetic change. Often, many do not even suspect about their genetics, since at first glance they are absolutely healthy. Only when they encounter problems during conception or gestation during pregnancy do they find out about it.

It would seem that healthy parents can identify a genetic pathology by donating blood for karyotyping analysis.

Analysis is given once in a lifetime. Karyotyping of spouses shows the complete set of chromosomes embedded in the genes. From the biology lessons of the school curriculum, everyone knows that women have a set of chromosomes equal to 46XX, and men - 46XY. Sometimes the set of chromosomes changes. This leads to the impossibility of procreation.

2. Infectious diseases of spouses.

The most dangerous and serious infectious diseases- this is rubella, herpes infection, CMV (cytomegalovirus infection), toxoplasmosis, and sexually transmitted infections: trichomoniasis, gonorrhea infection, ureaplasmosis, chlamydia and mycoplasmosis. A number of latent infections in a woman's body must be examined before the start.for when detecting sexually transmitted infections, go for a full course of treatment for both spouses. Then plan your next pregnancy.

These factors are so can affect the flow pregnancy.

A lack of progesterone or an excess of male sex hormones in the body of a pregnant woman can provoke a miscarriage.Women who produce too much or too little insulin (diabetes mellitus) or thyroid hormone are much more likely to have a miscarriage.

There are also indirect causes of non-developing pregnancy.

These include:

4. Violation of the blood coagulation system leads to uterine dysfunction. placental blood flow, to the formation of blood clots and damage to the placentaand its improper development and functioning, therefore, the embryo or already the fetus will receive an insufficient amount of nutrients, which will lead to a developmental delay and its death.

5. Drinking alcohol and smoking, which are easilyenter the embryo through the blood. The influence of alcohol and smoking is especially harmful in the early stages of pregnancy, when the future organs of the baby are laid.

6. Obesity or underweight during pregnancy- anotherpredisposing factor for miscarriage.

With increased or insufficientbody weight occurs hormonal disbalance. So steroid hormones accumulate in adipose tissue, which interfere with the development and bearing of the unborn child. With a lack of weight, a woman's body, on the contrary, is not able to produce the necessary amount of hormones and necessary substances - for the development of a normal pregnancy. There is a risk of miscarriage.

7. Use before pregnancy planning or duringpregnancy medicines, which can provoke a non-developing pregnancy. A certain group of drugs has a dangerous ability to accumulate in the tissues of the embryo, causing its pathological development.

Chemical substances have a detrimental effect on the embryo. For example, if a woman works in a hazardous industry and she has to come into contact with vapors of harmful substances.

8. In case of pregnancy that occurred during the IVF program, the risk ofnon-developing pregnancy is several times higher. Since women with problems conceiving or carrying a pregnancy are already preparing for the procedure from the very beginning.

9. Multiple pregnancies are a risk of missedpregnancy, since the body of a pregnant woman is assigned two or even three times more load. At multiple pregnancy it is more difficult to diagnose the onset of the death of one of the fetuses in the early stages.

To reduce the likelihood of a missed pregnancy, expectant mothers and fathers need to conduct a timely examination of the body before starting pregnancy planning.